Thermo Fisher Scientific ERCC6L Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human ERCC6L (aa 35-84). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERCC6L,uniProtId:Q2NKX8-1,ncbiNodeId:9606,antigenRange:35-84,antigenLength:1250,antigenImageFileName:PA5-44670_ERCC6L_Q2NKX8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-44670_ERCC6L_Q2NKX8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2607626

Product Specific Information

Peptide sequence: GDLEEAFKLF NLAKDIFPNE KVLSRIQKIQ EALEELAEQG DDEFTDVCNS

Sequence homology: Cow: 93%; Dog: 93%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 93%; Rat: 79%

Target Information

ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.