Thermo Fisher Scientific FGR Polyclonal Antibody
FGR 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, Western blot에 적합합니다. 인간, 개, 쥐에서 반응 예측되며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (TSAEPQYQPGDQT) corresponding to the C-terminus amino acids of FGR (aa 517–529) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983512 |
Product Specific Information
This antibody is predicted to react with canine, human, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
FGR is a SRC-related kinase present in hematopoietic cells. It signals within multiple pathways including the integrin pathway and downstream of chemokine and cytokine receptors.
This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains that mediate protein-protein interactions with phosphotyrosine-containing and proline-rich motifs.
It localizes to plasma membrane ruffles and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway.
Infection with Epstein-Barr virus results in overexpression of this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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