Thermo Fisher Scientific RELM beta Polyclonal Antibody
Mouse RELM beta 단백질(잔기 32-46)에 반응하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific RELM beta Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:10–1:500 |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 |
| Flow Cytometry (Flow) | 1:10–1:1,000 |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Reacts with residues 32–46 of the mouse RELM beta protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718788 |
Target Information
Adipose tissue is an energy reserve that is strictly regulated in animals. Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin.
Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine specifically secreted by adipocytes. It has suggested paracrine roles and a possible link to type 2 diabetes. Studies indicate that resistin levels are increased in obese, diabetic mice, antagonizing insulin action and inducing insulin resistance and glucose intolerance.
Resistin gene expression requires C/EBP alpha, and coactivators CBP and p300 acetylate histones at the resistin promoter, activating chromatin for transcription. PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(관련 항원 이미지: PA5-72934_RELM_beta_Q99P86-1_Rabbit.svg / PA5-72934_RELM_beta_Q99P86-1_Rabbit_PDP.jpeg)
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