Thermo Fisher Scientific PAPPA Monoclonal Antibody (5H9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:2,000

-

ELISA (ELISA)

1:100-1:2,000

-

Immunoprecipitation (IP)

1:10-1:500

-

Product Specifications

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

5H9

Immunogen

Purified human PAPPA.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_2159347

Product Specific Information

This antibody works well in htPAPP-A and dPAPP-A (PAPP-A dimer) immunoassays.

Target Information

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down`s syndrome (trisomy 21).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.