Thermo Fisher Scientific PAPPA Monoclonal Antibody (5H9)
PAPPA 단백질을 인식하는 Mouse IgG2b 단클론 항체. Western blot, ELISA, IP 등 다양한 면역분석에 적합. htPAPP-A 및 dPAPP-A 면역분석에서 우수한 성능. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| ELISA | 1:100–1:2,000 |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H9 |
| Immunogen | Purified human PAPPA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2159347 |
Product Specific Information
This antibody works well in htPAPP-A and dPAPP-A (PAPP-A dimer) immunoassays.
Target Information
Pregnancy-associated plasma protein-A (PAPP-A, also known as Insulin-like growth factor binding protein-4 protease or PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, originally discovered in serum from pregnant women. The heterotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first-trimester biochemical screening are used as a marker of Down’s syndrome (trisomy 21).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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