Thermo Fisher Scientific GPATCH3 Polyclonal Antibody
GPATCH3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Human, Mouse, Rat에 반응하며 WB, IHC, ICC/IF, ELISA 등에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GPATCH3, amino acids 331–430 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GPATCH3 is a protein coding gene involved in transcriptional regulation. It activates transcription from the CXCR4 promoter and may control neural crest cell migration related to ocular and craniofacial development. It also acts as a negative regulator of immune antiviral response via down-regulation of RIG-I-like receptor signaling and inhibition of type I interferon production. The mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream antiviral proteins such as TBK1 and TRAF6.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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