Thermo Fisher Scientific MMP14 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로 Western blot에 적합. Antigen affinity chromatography로 정제되었으며, PBS buffer(20% glycerol) 내 1.7 mg/mL 농도로 제공. MMP14 단백질 검출 및 종양 침윤 연구에 유용.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Human MMP14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792880 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Pig (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%).
- Positive Control: U87-MG, Neuro2A, MMP14-transfected 293T.
- Centrifuge briefly prior to opening the vial.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes such as arthritis and metastasis.
Most MMPs are secreted as inactive proproteins activated by extracellular proteinases.
The MMP14 gene encodes a membrane-type MMP (MT-MMP) containing a transmembrane domain, suggesting cell surface expression. This protein activates MMP2 and may play a role in tumor invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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