Thermo Fisher Scientific PAX7 (Rhabdomyosarcoma Marker) Monoclonal Antibody (PAX7/1187)
PAX7 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, 근육종 마커 연구에 적합. 파라핀 또는 PFA 고정 조직의 면역조직화학(IHC)에 사용 가능. 인간 반응성, 마우스 IgG1 항체. 고순도 Protein A/G 정제, PBS 버퍼 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PAX7/1187 |
| Immunogen | Recombinant fragment (aa301–505) of human PAX7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth.
The specific function of the paired box 7 gene is unknown but is speculated to involve tumor suppression, as fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma.
Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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