Thermo Fisher Scientific RASD2 Monoclonal Antibody (OTI1D11), TrueMAB
RASD2 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D11). Western blot과 Flow cytometry에 적합하며, HEK293T 세포에서 발현된 human RASD2 full-length 단백질을 면역원으로 제작됨. 동결건조 형태로 제공되며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D11 |
| Immunogen | Full length human recombinant protein of human RASD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Rhes (also known as tumor endothelial marker 2, TEM2) is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding proteins and is involved in brain development and function.
Mice lacking this gene exhibit increased anxiety and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes upregulated in tumor endothelium.
Tumor endothelial markers are significantly upregulated during angiogenesis and neoangiogenesis, essential for solid tumor growth. TEMs conserved across species and localized on the cell surface are of interest for anti-angiogenic therapy development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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