Thermo Fisher Scientific NSE2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NSE2 (NSMCE2) for ICC/IF applications. Recombinant protein immunogen, antigen affinity purified, supplied as liquid in PBS with glycerol. For research use only.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NSMCE2 (Recombinant protein control fragment Product #RP-104928) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664447 |
Product Specific Information
Immunogen sequence:
SQTNFTCPITK EEMKKPVKNK VCGHTYEEDA IVRMIESRQK RKKKAYCPQI GCSHTDIRKS DLIQDEALRR AIENHNKK
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 84%
Target Information
This gene encodes the large subunit of DNA damage-binding protein, a heterodimer composed of large and small subunits. The protein functions in nucleotide-excision repair, and its defective activity causes repair defects in patients with xeroderma pigmentosum complementation group E (XPE). Mutation analysis is required to confirm whether the XPE defect is in this gene or in the gene encoding the small subunit. Best vitelliform macular dystrophy is mapped to the same region (11q), but no sequence alterations of this gene are demonstrated in Best disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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