Thermo Fisher Scientific CD97 Monoclonal Antibody (5D5)
CD97 단백질을 표적으로 하는 Mouse IgG2a 단일클론 항체로 인간 시료에 반응. Western blot 및 ELISA에 최적화되어 있으며, PBS 용액 상태로 제공. 연구용으로 T세포 조절과 백혈구 항상성 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D5 |
| Immunogen | CD97 (NP_510966, 421–529 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KKQAELEEIY ESSIRGVQLR RLSAVNSIFL SHNNTKELNS PILFAFSHLE SSDGEAGRDP PAKDVMPGPR QELLCAFWKS DSDRGGHWAT EGCQVLGSKN GSTTCQCSH
Target Information
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor constitutively expressed on granulocytes and monocytes, and rapidly upregulated on T and B cells upon activation.
It is produced in alternatively spliced forms, and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage.
Interaction of CD97 on leukocytes and CD55 on vessel cells facilitates leukocyte activation and migration into tissues.
CD97 also plays roles in tumor migration, invasiveness, T cell regulation, and peripheral granulocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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