Thermo Fisher Scientific MAD3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human MAD3 protein. Validated for Western blot applications. Supplied as liquid, unconjugated form in PBS with glycerol. Suitable for research use only, not for diagnostic purposes.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human MAD3 (amino acids 141–169, UniProt ID: Q9BW11-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691508 |
Target Information
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX, which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX–MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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