Thermo Fisher Scientific NFYC Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NFYC protein. Validated for ICC/IF applications. Antigen affinity purified and supplied in PBS with glycerol. Suitable for research use only, not for diagnostic purposes.
- 카탈로그번호
- PA565917
- 판매단위
- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NFYC. Recombinant protein control fragment (Product #RP-106594) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663273 |
Product Specific Information
Immunogen sequence:
EPVQYYFTLAQ QPTAVQVQGQ QQGQQTTSST TTIQPGQIII AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSGTG QTMQVMQQII TNTGEIQQIP VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQ
- Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 100%
Target Information
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y consists of three subunits: NF-YA, NF-YB, and NF-YC. All three components are required for DNA binding.
Each NF-Y subunit contains a conserved segment necessary for NF-Y–DNA complex formation, homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of NF-YB and NF-YC interact through a histone-fold “handshake” motif similar to histone proteins H2B and H2A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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