Thermo Fisher Scientific TSPYL5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:5,000-1:10,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TSPYL5. Recombinant protein control fragment (Product #RP-88800). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TSPYL5,uniProtId:Q86VY4-1,ncbiNodeId:9606,antigenRange:268-389,antigenLength:417,antigenImageFileName:PA5-56710_TSPYL5_Q86VY4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56710_TSPYL5_Q86VY4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649017

Product Specific Information

Immunogen sequence: SQEKEVLSYL NSLEVEELGL ARLGYKIKFY FDRNPYFQNK VLIKEYGCGP SGQVVSRSTP IQWLPGHDLQ SLSQGNPENN RSFFGWFSNH SSIESDKIVE IINEELWPNP LQFYLLSEGA RV

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 88%.

Target Information

Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.