Thermo Fisher Scientific CHMP2B Monoclonal Antibody (M1)
CHMP2B 단백질을 인식하는 Mouse IgG1 단클론 항체로 ELISA에 적합. 인간 시료 반응성 확인됨. GST 태그가 포함된 full-length CHMP2B 단백질을 면역원으로 사용. PBS 기반 액상 형태, 방부제 없음. -20°C 보관 권장.
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Applications
- ELISA (ELISA)
Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M1 |
| Immunogen | CHMP2B (AAH01553.1, 1–213 a.a.) full-length recombinant protein with GST tag (GST MW: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD
Target Information
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein.
It is widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta, and leukocytes.
CHMP2B associates directly with CHMP2A and VPS4 for the disassembly of the ESCRT-III complex.
Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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