Thermo Fisher Scientific p75NTR Monoclonal Antibody (MC192)
Rat p75NTR 단백질을 인식하는 단클론 항체로, Western blot, IHC, ELISA 등 다양한 응용에 사용 가능. Mouse IgG1 아이소타입이며 비결합형 상태로 제공. 신경 성장 인자 수용체 연구 및 신경계 발달 연구에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5–15 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | Assay-dependent | - |
| ELISA | 5–15 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MC192 |
| Immunogen | Nerve growth factor receptor (TNFR superfamily, member 16) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: rat p75NTR.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo.
Antibodies reacting specifically with NGFR p75 are valuable tools for the detection and characterization of NGFR p75, enhancing our understanding of neuronal development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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