Thermo Fisher Scientific OTOR Polyclonal Antibody
Rabbit polyclonal antibody targeting human OTOR, validated for WB and IHC(P) applications. Recombinant protein immunogen, antigen affinity purified. Supplied as liquid in PBS with glycerol and sodium azide. For research use only.
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Thermo Fisher Scientific OTOR Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OTOR. Recombinant protein control fragment (Product #RP-90188). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645111 |
Product Specific Information
Immunogen sequence:
RLASKKLCAD DECVYTISLA SAQEDYNAPD CRFINVKKGQ QIYVYSKLVK ENGAGEFWAG SVYGDGQDEM GVVGYFPRNL VKEQRVYQEA TKEVPTTDID FFCE
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 89%
Target Information
OTOR, also called Otoraplin and MIAL, is a secreted cytokine of the MIA/OTOR family. Members of this family, including MIA, MIA2, and TANGO, share a Src homology-3 (SH3)-like domain. OTOR is predominantly expressed in the cochlea of the inner ear, and to a lesser extent in fetal brain tissue and some cartilage tissues. It appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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