Thermo Fisher Scientific CRLF2 Polyclonal Antibody
CRLF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도의 Protein A 정제 방식으로 제조. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CRLF2, amino acids 81–180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thymic stromal lymphopoietin (TSLP) is an important factor that drives dendritic cell maturation and activation. It participates in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis, and induction of CD4+ T cell-mediated allergic reactions. TSLP also supports the growth and differentiation of fetal liver and adult B cell progenitors to the IgM-positive stage. Its receptor, TSLP-R, binds TSLP with low affinity; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and formation of a functional heteromeric complex. This receptor complex requires STAT5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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