Thermo Fisher Scientific NENF Polyclonal Antibody
Rabbit polyclonal antibody targeting human NENF protein. Validated for Western blot at 1 µg/mL. Recognizes N-terminal region (aa 38–87) with high species homology. Supplied as liquid, 0.5 mg/mL in PBS with 2% sucrose and 0.09% sodium azide. Store at -2...
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Applications
- Western Blot (WB): Tested at 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human NENF (aa 38–87) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576532 |
Product Specific Information
- Peptide sequence:
AERGPPVRLF TEEELARYGG EEEDQPIYLA VKGVVFDVTS GKEFYGRGAP - Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Target Information
NENF is a secreted protein expressed in neurons but not glial cells of the brain. It exhibits neurotrophic activity in primary cultured mouse neurons but lacks mitogenic activity in astrocytes. NENF activates MAP and PI3K pathways, inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting action via a Gi/Go-protein-coupled receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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