Thermo Fisher Scientific Kininogen-1 heavy chain Polyclonal Antibody
인간 Kininogen-1 heavy chain을 인식하는 토끼 폴리클로날 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. KLH 결합 합성 펩타이드(aa 281-356)를 면역원으로 제작. 단백질 A로 정제된 액상 항체이며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Kininogen-1 heavy chain (amino acids 281–356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene uses alternative splicing to generate two different proteins: high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK).
HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Bradykinin, a peptide causing numerous physiological effects, is released from HMWK.
In contrast, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: BS-7688R_Kininogen_Heavy_Chain_P01042-1_Rabbit.svg, BS-7688R_Kininogen_Heavy_Chain_P01042-1_Rabbit_PDP.jpeg)
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