Thermo Fisher Scientific mGluR4 Monoclonal Antibody (OTI6D1)
Human mGluR4 단백질을 인식하는 Mouse monoclonal antibody로, WB 및 IHC(P) 실험에 최적화됨. Unconjugated 형식이며, 1 mg/mL 농도로 PBS/BSA/glycerol 용액에 보관. 뇌 신경전달 관련 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 126–407 of GRM4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724687 |
Target Information
The Metabotropic Glutamate Receptor mGluR4 (GRM4) binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors divided into three groups based on sequence homology, signal transduction mechanisms, and pharmacologic properties.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-27293_mGluR4_Q14833-1_House_mouse.svg, MA5-27293_mGluR4_Q14833-1_House_mouse_PDP.jpeg)
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