Thermo Fisher Scientific MEK2 Polyclonal Antibody
MEK2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 및 50% 글리세롤 용액 형태로 제공되며, -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Mitogen Activated Protein Kinase 2 (amino acids 86–331 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903786 |
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that plays a critical role in mitogen growth factor signal transduction. MEK2 (also known as MAPKK2) activates ERK1/2 and MAPK enzymes by phosphorylating residues within the TEY motif in the activation loop. MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, serving as a negative feedback mechanism to suppress MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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