Thermo Fisher Scientific SLC27A2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1 µg/mL
• View 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 5 µg/mL
• View publications

Product Specifications

Product Specific Information

• Peptide sequence:
  LLFRDETLTY AQVDRRSNQV ARALHDHLGL RQGDCVALLM GNEPAYVWLW

• Sequence homology:
  Cow: 93%
  Dog: 93%
  Guinea Pig: 92%
  Horse: 93%
  Human: 100%
  Mouse: 100%
  Pig: 100%
  Rabbit: 93%
  Rat: 100%

Target Information

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, playing a key role in lipid biosynthesis and fatty acid degradation.
This isozyme activates long-chain, branched-chain, and very-long-chain fatty acids (≥22 carbons) to their CoA derivatives. It is expressed primarily in liver and kidney, localized in the endoplasmic reticulum and peroxisomes but not in mitochondria.
Decreased peroxisomal enzyme activity contributes to the biochemical pathology in X-linked adrenoleukodystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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