Thermo Fisher Scientific MALSU1 Polyclonal Antibody
Thermo Fisher Scientific의 MALSU1 폴리클로날 항체로 인간 시료에 반응하며, IHC 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 미토콘드리아 리보솜 기능 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MALSU1. Recombinant protein control fragment (Product #RP-92768) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643708 |
Product Specific Information
Immunogen sequence:
GSAVGAEPGL RLLAVQRLPV GAAFCRACQT PNFVRGLHSE PGLEERAEGT VNEGRPESDA ADHTGPKFDI DMMVSLLRQE NARDICVIQV PPEMRYTDYF VIVS
- Highest antigen sequence identity to the following orthologs:
- Mouse: 60%
- Rat: 59%
Target Information
Required for normal mitochondrial ribosome function and mitochondrial translation (PubMed:22238375, PubMed:23171548).
May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable).
Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable).
Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable).
May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (PubMed:22238376, PubMed:23171548).
May function as a ribosomal silencing factor (Probable). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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