Thermo Fisher Scientific KCNH2 Polyclonal Antibody
KCNH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 인간 및 다양한 동물 종에서 높은 반응성을 보이며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human KCNH2 (aa 895–944) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690269 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% | Dog: 86% | Guinea Pig: 86% | Horse: 93% | Human: 100% | Mouse: 100% | Pig: 93% | Rabbit: 100% | Rat: 100%
Target Information
Human ether-a-go-go related gene (HERG) encodes the pore-forming alpha subunit of the delayed rectifier potassium channel IKr.
There are two N-terminal splice variants of HERG:
- Isoform 1 alpha (full-length)
- Isoform 1 beta (shorter, lacks PAS motif and deactivates faster)
Residues within the C-terminal region play roles in channel expression and gating, including voltage-dependent activation.
HERG is expressed primarily in the heart, more abundantly in the ventricles than in the atria.
Mutations in HERG are associated with inheritable long QT syndrome type 2 and short QT syndrome type 1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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