Thermo Fisher Scientific TCL1A Recombinant Rabbit Monoclonal Antibody (PD00-94)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:2,000

-

Immunocytochemistry (ICC/IF)

1:50

-

Flow Cytometry (Flow)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PD00-94

Immunogen

Synthetic peptide aa 1-114/114. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TCL1A (TCL1),uniProtId:P56279-1,ncbiNodeId:9606,antigenRange:1-114,antigenLength:114,antigenImageFileName:MA5-50732_TCL1A_TCL1_P56279-1_Rabbit.svg,antigenImageFileNamePDP:MA5-50732_TCL1A_TCL1_P56279-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3092880

Product Specific Information

Positive control: Daudi cell lysates, human tonsil tissue, human appendix tissue, PC-3, Daudi.

Predicted band size: 13 kDa

Subcellular Location: Cytoplasm, Nucleus, Microsome, Endoplasmic reticulum.

Target Information

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (summarized by Virgilio et al., 1998). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.