Thermo Fisher Scientific FPR1 Polyclonal Antibody
FPR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 제공되며 인체 및 설치류 등 다양한 종에 반응합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 150–200 on N-formyl peptide receptor (FPR1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils, and monocytes. It is a seven-transmembrane pertussis toxin-sensitive GPCR that binds formylated peptides generated by bacteria, resulting in leukocyte trafficking to sites of inflammation. Ligand binding to FPR activates multiple effectors including phospholipase C, leading to calcium mobilization and PKC activation. FPR signaling also influences actin cytoskeleton polarization, integrin activation, cell migration, phagocytosis, degranulation, and release of reactive oxygen intermediates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: FPR1-101AP_FPR1_P21462-1_Rabbit.svg, FPR1-101AP_FPR1_P21462-1_Rabbit_PDP.jpeg)
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