Thermo Fisher Scientific CLCN3 Polyclonal Antibody
Rabbit polyclonal antibody against CLCN3 protein. Validated for WB, IHC, ICC/IF, and IP applications. Lyophilized form with 0.8 mg/mL concentration. Suitable for research use in neuronal function and vesicle trafficking studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | GST fusion protein with amino acid residues 592–661 of rat CLC-3 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735664 |
Product Specific Information
- Shipped at room temperature as a lyophilized powder.
- Store at -20 °C upon receipt.
- Reconstitution: Add 50 µL of deionized water.
Target Information
CLCN3 mediates the exchange of chloride ions against protons, functioning as an antiporter that contributes to acidification of endosomes and synaptic vesicles.
It may affect vesicle trafficking and exocytosis, playing an important role in neuronal cell function and short-term memory regulation through protein kinase C-mediated pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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