Thermo Fisher Scientific AGL Polyclonal Antibody
Rabbit polyclonal antibody recognizing human AGL protein. Validated for IHC(P) and ICC/IF applications. Supplied as a liquid, unconjugated form at 0.1 mg/mL. Suitable for glycogen metabolism research. For research use only.
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- PA555880
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AGL. Recombinant protein control fragment (Product # RP-94404) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637761 |
Product Specific Information
Immunogen sequence:
EVYLRRELIC WGDSVKLRYG NKPEDCPYLW AHMKKYTEIT ATYFQGVRLD NCHSTPLHVA EYMLDAARNL QPNLYVVAEL FTGSEDLDNV FVTRLGISSL
Sequence identity to orthologs:
- Mouse: 95%
- Rat: 96%
Target Information
This gene encodes the glycogen debrancher enzyme involved in glycogen degradation. It has two independent catalytic activities:
- 4-alpha-glucotransferase activity
- Amylo-1,6-glucosidase activity
Mutations in this gene are associated with glycogen storage disease, with variable enzymatic and clinical presentations possibly due to tissue-specific alternative splicing. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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