Thermo Fisher Scientific ARFGAP1 Polyclonal Antibody
ARFGAP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 면역세포화학(ICC/IF)에 사용 가능. 인간, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제된 액상 형태로, 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARFGAP1 (Accession Q8N6T3), corresponding to amino acid residues D303–D353 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850844 |
Product Specific Information
This antibody detects endogenous levels of total ARFGAP1.
Target Information
ArfGAP1 is a 406-amino-acid regulatory protein containing an Arf-GAP domain involved in activating the GTPase activity of ADP ribosylation factor (ARF). It acts as a GTPase-activating protein (GAP) for ARF1, promoting the hydrolysis of ARF1-bound GTP and facilitating dissociation of coat proteins from Golgi-derived membranes and vesicles. This process is essential for vesicle fusion with target compartments. ArfGAP1 activity is stimulated by phosphoinositides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported, and ArfGAP1 is ubiquitously expressed across most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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