Thermo Fisher Scientific Lamin B Receptor Polyclonal Antibody
Lamin B Receptor를 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도 Affinity 정제 및 PBS buffer로 안정화되어 있습니다. 핵막 단백질 연구용으로 권장됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LBR (Accession Q14739), corresponding to amino acid residues A332–D382 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852168 |
Product Specific Information
Antibody detects endogenous levels of total LBR.
Target Information
The protein encoded by this gene belongs to the ERG4/ERG24 family. It is localized in the nuclear envelope inner membrane and anchors the lamina and heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene have been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus, and two transcript variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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