Thermo Fisher Scientific Prostate Specific Antigen (PSA) Monoclonal Antibody (KLK3, 1248)
인체 PSA 단백질을 인식하는 마우스 단클론 항체로, IHC(P) 실험에 적합합니다. 고순도의 Protein A/G 정제 항체이며, PBS 버퍼(0.05% BSA, 0.05% sodium azide)에 보관됩니다. 4°C에서 저장하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KLK3, 1248 |
| Immunogen | Recombinant full-length human KLK3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- For formalin-fixed tissues: Heat tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
PSA (Prostate Specific Antigen) is a chymotrypsin-like serine protease belonging to the kallikrein family, produced by the prostate epithelium and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma, predominantly complexed with alpha-1-antichymotrypsin (ACT). A higher proportion of PSA-ACT complexes is observed in prostate cancer compared to benign prostatic hyperplasia. PSA is widely used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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