Thermo Fisher Scientific Phosphotyrosine (P-Tyr) Monoclonal Antibody (PY793)
세포 내 단백질의 인산화된 티로신 잔기를 검출하는 단클론 항체. 다양한 면역조직화학, 면역세포화학 및 유세포분석에 사용 가능. 높은 특이성과 재현성을 제공하며, 연구용으로 최적화됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PY793 |
| Immunogen | Phosphotyrosine conjugated to BSA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tyrosine phosphorylation plays a key role in signal transduction from transmembrane receptors and in oncogene tyrosine kinase-mediated transformation. It is a primary mechanism for regulating mitogenesis, cell cycle progression, and oncogenic transformation. Antibodies that specifically recognize phosphorylated tyrosine residues are essential tools for studying tyrosine-phosphorylated proteins and their associated biochemical pathways. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is particularly useful for detecting P-Tyr proteins in immunohistochemical and immunocytochemical assays where secondary antibody use may complicate detection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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