Thermo Fisher Scientific CCR3 Polyclonal Antibody
CCR3 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트에 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 용액에 0.02% sodium azide가 포함되어 있으며, 2–8°C 보관 권장.
- 카탈로그번호
- PA519861
- 판매단위
- pk
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Applications and Tested Dilution
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the amino terminus of human CCR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154507 |
Product Specific Information
- A suggested positive control is human spleen tissue lysate.
- PA5-19861 can be used with blocking peptide PEP-0304.
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta.
CCR3 transduces a signal by increasing intracellular calcium ion levels and also serves as an alternative co-receptor with CD4 for HIV-1 infection.
Chemokines play key roles in inflammation and immune cell recruitment, activating leukocytes via G protein-coupled receptors.
Chemokine receptor subtypes are divided into two major groups, CXCR and CCR, based on chemokine class.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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