Thermo Fisher Scientific NXF3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.25 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

4-8 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the C-terminal of human NXF3 (aa 435-484). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NXF3,uniProtId:Q9H4D5-1,ncbiNodeId:9606,antigenRange:435-484,antigenLength:531,antigenImageFileName:PA5-41871_NXF3_Q9H4D5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-41871_NXF3_Q9H4D5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2605418

Product Specific Information

Peptide sequence: SSFLVDMWYQ TEWMLCFSVN GVFKEVEGQS QGSVLAFTRT FIATPGSSSS

Sequence homology: Cow: 92%; Dog: 92%; Guinea Pig: 77%; Horse: 79%; Human: 100%; Pig: 92%; Rabbit: 92%; Rat: 77%

Target Information

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.