Thermo Fisher Scientific GPNMB Monoclonal Antibody (OTI8A10), TrueMAB
인간 GPNMB 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot 및 IHC(Paraffin) 적용 가능. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol 버퍼에 보존. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A10 |
| Immunogen | Full length human recombinant protein of human GPNMB produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein.
GPNMB shows expression in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic cell lines.
It may be involved in growth delay and reduction of metastatic potential.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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