Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Gephyrin 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 사용 가능. Mouse에서 검증되었으며, Human, Chicken, Xenopus에서도 반응 예측. 액상 형태로 제공되며 4°C 또는 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1 µg/mL | View 1 publication |
Product Specifications
| Specification | Details |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 700 to the C-terminus of Mouse Gephyrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_10984155 |
Product Specific Information
This antibody is predicted to react with chicken, human, and Xenopus laevis based on sequence homology.
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to receptor subunit domains and tubulin dimers.
In non-neuronal tissues, this protein is also required for molybdenum cofactor biosynthesis.
Mutations in the GPHN gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Multiple alternatively spliced transcript variants encoding different isoforms have been described, though not all full-length variants are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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