Thermo Fisher Scientific CSF3 Monoclonal Antibody (OTI1C7), TrueMAB

Thermo Fisher Scientific CSF3 Monoclonal Antibody (OTI1C7), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000
Publications: -

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

G-CSF (Granulocyte Colony Stimulating Factor) is a cytokine that stimulates the production and antibacterial function of neutrophils and monocytes.
Human G-CSF is an 18.8 kDa protein containing 175 amino acids. It is produced by activated monocytes, macrophages, endothelial cells, fibroblasts, astrocytes, osteoblasts, and bone marrow cells.
G-CSF influences proliferation, differentiation, and activation of hematopoietic cells and is expressed by various transformed cells such as carcinoma and myeloblastic leukemia cells.
It is encoded by two distinct DNA sequences resulting in isoforms with different activity levels.
Clinical applications include treatment of neonatal infections, myocardial infarction, neutropenia, severe infections, sepsis, chronic autoimmune neutropenia, acute myeloid leukemia, Sweet’s syndrome, and AIDS.
G-CSF dysfunction is linked to Kostmann Syndrome and serves as a marker for certain carcinomas such as bladder cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.