Thermo Fisher Scientific CCR10 Polyclonal Antibody
Thermo Fisher Scientific CCR10 Polyclonal Antibody는 인간 CCR10 단백질을 인식하는 토끼 IgG 폴리클로날 항체로, IHC(P) 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 0.1% sodium azide를 함유한 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 3–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from C-terminus of human CCR10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1956913 |
Product Specific Information
PA1-32571 detects GPCR GPR2/CCR10 from human samples.
Target Information
Chemokines are a group of small (approximately 8–14 kD), mostly basic, structurally related molecules that regulate the trafficking of various leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. They play key roles in immune system development, homeostasis, and function, and affect cells of the central nervous system and endothelial cells involved in angiogenesis or angiostasis.
Chemokines are divided into two major subfamilies, CXC and CC, based on the arrangement of the first two of the four conserved cysteine residues. In CXC chemokines, the two cysteines are separated by a single amino acid; in CC chemokines, they are adjacent.
CCR10 is the receptor for CCL27. The CCR10–CCL27 interaction is involved in T cell-mediated skin inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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