Thermo Fisher Scientific Integrin Alpha V Polyclonal Antibody
다양한 종(Human, Mouse, Rat)에 반응하는 Integrin Alpha V 폴리클로날 항체. Western blot, IHC, ICC, Flow cytometry 등 다중 응용에 적합. Rabbit IgG 기반으로 Protein A 정제. 고순도 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 – 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100 – 1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100 – 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 – 1:500 |
| Flow Cytometry (Flow) | 1:10 |
| ELISA | 1:500 – 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Integrin Alpha V (amino acids 901–1048) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Gene: ITAGV
Protein: Integrin alpha V (CD51)
Integrins are heterodimeric integral membrane proteins composed of an alpha and a beta chain. The alpha V subunit forms disulfide-linked heavy and light chains that associate with multiple beta chains (β1, β3, β5, β6, β8) to form various integrins. Among these, the αVβ3 integrin, also known as the Vitronectin receptor (VNR), is well studied for its role in cell adhesion and signal transduction. Integrin β3 is also found with the αIIb chain in platelets and participates in cell adhesion and surface-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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