Thermo Fisher Scientific MAGEA11 Polyclonal Antibody
MAGEA11 단백질을 인식하는 Rabbit Polyclonal 항체로 인간 및 랫트 반응성. Western blot 및 IHC(Paraffin) 실험에 적합하며, 고순도 Affinity chromatography 정제. PBS/glycerol buffer에 보관하며 -20°C 저장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAGEA11 (Accession P43364), corresponding to amino acid residues P388–V429 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818702 |
Product Specific Information
Antibody detects endogenous levels of total MAGEA11.
Target Information
MAGEA11 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50–80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls.
The MAGEA genes are expressed at a high level in a number of tumors of various histologic types and are silent in normal tissues except testis and placenta.
The MAGEA genes are clustered on chromosome Xq28 and may be implicated in hereditary disorders such as dyskeratosis congenita.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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