Thermo Fisher Scientific GBA Recombinant Rabbit Monoclonal Antibody (ARC0500)
Thermo Fisher Scientific의 GBA Recombinant Rabbit Monoclonal Antibody (ARC0500)는 인간 및 랫트 시료에서 GBA 단백질 검출에 사용됩니다. Western blot, IHC, ELISA에 적합하며, 높은 특이성과 재현성을 제공합니다. HEK293 세포에서 생산된 recombinant monoclonal 항체로 연구용에 최적화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0500 |
| Immunogen | Synthetic peptide corresponding to amino acids 437–536 of human Glucosylceramidase beta (GBA) (P04062) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849139 |
Product Specific Information
Immunogen sequence:
VDSPIIVDIT KDTFYKQPMF YHLGHFSKFI PEGSQRVGLV ASQKNDLDAV ALMHPDGSAV VVVLNRSSKD VPLTIKDPAV GFLETISPGY SIHTYLWRRQ
Target Information
GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disorder characterized by accumulation of glucocerebrosides. A related pseudogene is located approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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