
Thermo Fisher Scientific SCP2 Monoclonal Antibody (OTI1D2)
SCP2 단백질을 인식하는 Thermo Fisher monoclonal antibody로, Western blot과 IHC(파라핀 절편)에 적합합니다. 인간 시료에 반응하며, 고순도의 액상 항체로 안정적인 신호 검출이 가능합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D2 |
| Immunogen | Full length human recombinant protein of SCP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725302 |
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with both sharing a common C-terminus.
Evidence suggests that SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, while SCP2 functions as an intracellular lipid transfer protein.
This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, characterized by peroxisomal deficiency and impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants, some encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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