Thermo Fisher Scientific MTG16 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
PSFTPHTHRED GPATLPHGRF HGCLKWSMVC LLMNGSSHSP

Highest antigen sequence identity to the following orthologs:

• Mouse: 95%
• Rat: 95%

Target Information

This gene encodes a member of the myeloid translocation gene family which interacts with DNA-bound transcription factors and recruits a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia, producing a chimeric gene composed of the 5′ region of the runt-related transcription factor 1 gene fused to the 3′ region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in multiple transcript variants.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.