
Thermo Fisher Scientific CLCC1 Polyclonal Antibody
인간 CLCC1 단백질에 특이적인 Thermo Fisher Scientific의 rabbit polyclonal antibody. IHC(P) 및 ICC/IF 응용에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 0.2 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CLCC1. Recombinant protein control fragment (Product #RP-90166). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639851 |
Product Specific Information
Immunogen sequence:
PPQALRPRDR RRQEEIDYRP DGGAGDADFH YRGQMGPTEQ GPYAKTYEGR REILRERDVD LRFQTGNKSP EVLRAFDVPD AEAREHPTVV PSHKSPVLDT KPKE
Highest antigen sequence identity to orthologs:
- Mouse: 62%
- Rat: 64%
Target Information
Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-proteins like Ras. The NF1 gene is classified as a tumor suppressor gene, and mutations at the NF1 locus have been associated with neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation, and memory deficiency. Neurofibromin is also linked to intermediate filaments of the cytoskeleton, with highest expression during desmosome formation. Mutations of NF1 produce variable cell sizes and morphologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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