Thermo Fisher Scientific IL-3 Polyclonal Antibody

Applications

• ELISA (ELISA): 5–10 µg/mL

Product Specifications

Product Specific Information

• PA1-75208 specifically detects IL-3.
• Successfully used in ELISA applications.
• Immunogen: Recombinant IL-3.

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most of these functions are enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and the bioactivity of IL-3 is highly species-specific.
Human IL-3 has no activity on mouse cells.
IL-3 supports proliferation, differentiation, and apoptosis of various hematopoietic cells, and also exhibits neurotrophic activity that may be associated with neurological disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.