Thermo Fisher Scientific RASD2 Polyclonal Antibody
RASD2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 면역세포염색에 적합하며, 인간, 마우스, 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer 보존, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RASD2 (Accession Q96D21), corresponding to amino acid residues K120–E170 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850675 |
Product Specific Information
This antibody detects endogenous levels of total RASD2.
Target Information
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding proteins and is implicated in brain development and function. Mice lacking this gene show increased anxiety and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes upregulated in tumor endothelium. Tumor endothelial markers are significantly upregulated during angiogenesis and neoangiogenesis, processes crucial for solid tumor growth. TEMs conserved across species are of particular interest for anti-angiogenic therapy development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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