Thermo Fisher Scientific ACBD3 Monoclonal Antibody (OTI2B12), TrueMAB
ACBD3 단백질을 표적으로 하는 마우스 모노클로날 항체로, Western blot에 최적화되어 있습니다. HEK293T 세포에서 생산된 재조합 인간 단백질을 면역원으로 사용하며, 고순도 친화 크로마토그래피 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA504857
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B12 |
| Immunogen | Full length human recombinant protein of human ACBD3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
GOLPH1, also known as GCP60, is a Golgi protein that interacts with the integral membrane protein giantin and contributes to Golgi structure maintenance. It also interacts with Golgin-160, which can be cleaved by caspases-2, -3, and -7, leading to nuclear localization of Golgin-160 fragments. The interaction is regulated by the oxidation state of Cys-463 within GOLPH1. Additionally, GOLPH1 interacts with Numb, a signaling protein involved in asymmetric cell division of neural progenitor cells, suggesting that Golgi fragmentation and reconstitution may regulate Numb signaling and couple cell fate with cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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