Thermo Fisher Scientific TUBA3C/TUBA3E Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human TUBA3C/E, corresponding to a region within C-terminal amino acids. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TUBA3C/TUBA3E,uniProtId:P0DPH7-1,ncbiNodeId:9606,antigenRange:450,antigenLength:450,antigenImageFileName:PA5-106805_TUBA3CTUBA3E_P0DPH7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106805_TUBA3CTUBA3E_P0DPH7-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:TUBA3C/TUBA3E,uniProtId:Q6PEY2-1,ncbiNodeId:9606,antigenRange:450,antigenLength:450,antigenImageFileName:PA5-106805_TUBA3CTUBA3E_Q6PEY2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106805_TUBA3CTUBA3E_Q6PEY2-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2854473

Product Specific Information

Antibody detects endogenous levels of total TUBA3C/E.

Target Information

The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). Microtubules have their intrinsic polarity; highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening - this phenomenon is called dynamic instability of microtubules. The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.