Thermo Fisher Scientific UBE2B Monoclonal Antibody (OTI1E11), TrueMAB
UBE2B 단백질을 표적으로 하는 Mouse monoclonal antibody로 Western blot에 적합. 고순도 Affinity chromatography로 정제된 액상 형태이며, PBS/BSA/glycerol buffer에 보관. 단백질 유비퀴틴화 연구 및 DNA 손상 복구 관련 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Full length human recombinant protein of human UBE2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
UBE2B is a member of the E2 ubiquitin-conjugating enzyme family and is required for post-replicative DNA damage repair.
Its protein sequence is 100% identical to mouse, rat, and rabbit homologs, indicating that this enzyme is highly conserved in eukaryotic evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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