Thermo Fisher Scientific ESRRA Recombinant Rabbit Monoclonal Antibody (23GB5740)
Recombinant rabbit monoclonal antibody targeting human ESRRA (ERR alpha). Validated for Western blot applications. High specificity and reproducibility using HEK293F expression system. Supplied in liquid form with PBS/glycerol buffer for stable storage.
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Thermo Fisher Scientific ESRRA Recombinant Rabbit Monoclonal Antibody (23GB5740)
Applications
- Western Blot (WB): Tested dilution 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5740 |
| Immunogen | A synthesized peptide derived from human ERR alpha (1–28AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All ERR family members share an almost identical DNA-binding domain, showing 68% amino acid identity with that of the estrogen receptor. ERR1 binds to an ERR-alpha response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3'), interacts with the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1, and acts as an important regulator of the MCAD promoter. Studies indicate that ERR1 functions as a metabolic regulator and is expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA5-52902_ESRRA_P11474-1_Rabbit.svg)
(이미지: MA5-52902_ESRRA_P11474-1_Rabbit_PDP.jpeg)
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